Editorial: Genomic Characterization of Emerging Human Fungal Pathogens

Comparative Genomic Analysis of Human Fungal Pathogens Causing Paracoccidioidomycosis

Paracoccidioides is a fungal pathogen and the cause of paracoccidioidomycosis, a health-threatening human systemic mycosis endemic to Latin America. Infection by Paracoccidioides, a dimorphic fungus in the order Onygenales, is coupled with a thermally regulated transition from a soil-dwelling filamentous form to a yeast-like pathogenic form. To better understand the genetic basis of growth and ...

Emerging Threats in Antifungal-Resistant Fungal Pathogens

The use of antifungal drugs in the therapy of fungal diseases can lead to the development of antifungal resistance. Resistance has been described for virtually all antifungal agents in diverse pathogens, including Candida and Aspergillus species. The majority of resistance mechanisms have also been elucidated at the molecular level in these pathogens. Drug resistance genes and genome mutations ...

Editorial: Proteomics of Microbial Human Pathogens

Despite remarkable advances in treatment and prevention, infectious diseases remain amongst the leading causes of death worldwide, particularly in the developing world, and drug resistant pathogens are ominously on the rise. By way of one specific example, the global incidence of human tuberculosis (TB) disease—caused by infection with the pathogen Mycobacterium tuberculosis—is estimated to be ...

Molecular Identification of Human Fungal Pathogens

Emerging pathogens: fungal host jumps following anthropogenic introduction.

an important additional dimension. In birds, sexual dimorphism in singing and song learning varies greatly among species, and sex differences in brain morphology are the most extreme documented in any vertebrate [2,3]. Differences in female song-learning strategies might be even greater than those observed in male vocal learning, ranging from no learning to learning as much as males do [3,4]. S...